在一项随机对照试验中,饮食干预对大肠直肠癌患者体育活动的溢出效应
Hege Berg Henriksen1,2, Åshild Kolle3, Andreas Stenling4,5
1Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, P.O. Box 1049, 0316, Oslo, Norway. h.b.henriksen@medisin.uio.no.
概括
在结直肠癌患者的一年饮食干预没有显示出12个月后对体力活动的显著溢出效应. 这项研究旨在通过为两组人提供平等的体育活动支持来分离饮食影响.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 生活方式 医学 医疗
背景情况:
- 对饮食变化的随机对照试验 (RCT) 可能会被生活方式溢出效应所混.
- 将饮食干预与身体活动变化的影响隔离出来是很有挑战性的.
- 在CRC-NORDIET研究中,研究了手术后结直肠癌患者的溢出效应.
研究的目的:
- 调查一年的饮食干预对身体活动和功能的溢出效应.
- 为了比较饮食干预组和对照组之间的身体活动和功能变化.
- 为了分离饮食改变对结直肠癌幸存者的特定影响.
主要方法:
- 50-80岁的成年人被随机分为干预 (n=240) 或控制 (n=229) 组.
- 两组人都得到了相同的体育活动激励和指导.
- 使用活动传感器测量身体活动;在基线,6个月和12个月,通过手握,坐立和6分钟步行测试来评估身体功能.
主要成果:
- 与对照组相比,饮食干预组在6个月后 (每天0.18小时) 显示了中度至强度体力活动 (MVPA) 的显著增加.
- 在12个月内,MVPA的显著差异减少了0.10小时/天,而两组之间没有统计学上显著的差异.
- 身体功能指标从基线到6个月在两组都得到改善,在12个月没有进一步的增长.
结论:
- 在12个月初级终点时,饮食干预对体育活动没有显著的溢出效应.
- 为两组人提供统一的体力活动支持,有助于隔离饮食干预效应.
- 这种方法允许对二次癌症预防中的饮食影响和行为干预措施进行更清晰的分析.
关键词:
加速度计的速度计.行为行为行为.结肠直肠癌是一种癌症.通过饮食干预进行食干预.基于食物的饮食指南生活方式 生活方式国家指南 国家指南身体活动 身体活动物理功能 物理功能随机对照试验是随机对照试验.溢出效应是一种溢出效应.更多相关视频
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