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Updated: Jun 21, 2026

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples
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Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples

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对JPH2-Knockout心肌细胞的功能分析确定了ECCD作为人类心脏模型JPH2中的新型指标

Tianwei Guo1, Hongyue Wang1, Fujian Wu1

  • 1Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College/National Center for Cardiovascular Diseases, No. 167 Beilishi Road Xicheng District, Beijing, 100037, China.

Stem cell research & therapy
|May 9, 2025
PubMed
概括

克托菲林-2 (JPH2) 缺乏导致心力衰竭,因为它破坏了心脏激发 - 收缩的合. 一个新的指标,刺激 - 收缩合延迟 (ECCD),精确地测量这种损伤,提供治疗见解.

关键词:
心肌病是一种心肌病.激发 - 收缩合器人类胚胎干细胞衍生的心肌细胞.克托菲林2 克托菲林2

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High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers14:03

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