口腔呼吸与关节系统之间的关联:叙述审查
Liqun Gu1, Kuo Gai1, Xiangtao Liu1
1Department of Pediatric Dentistry, Stomatology Hospital, School of Stomatology, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, China.
Journal of oral rehabilitation
|May 9, 2025
概括
儿童慢性口腔呼吸 (MB) 可能对骨和肌肉功能发育产生负面影响,可能导致关节障碍 (TMD). 本综述探讨了MB和TMD之间的联系,详细介绍了潜在的机制和病理途径.
科学领域:
- 儿科牙科 儿科牙科
- 面部的发育 面部的发展
- 短关节疾病 短关节疾病
背景情况:
- 儿童慢性病态口腔呼吸 (MB) 与骨和肌肉功能发育的改变有关.
- 患有MB的儿童经常出现关节疾病 (TMD) 的症状,包括关节 (TMJ) 疼痛和功能障碍.
研究的目的:
- 审查口腔呼吸和儿童的TMD之间的相关性.
- 阐明MB对 temporomandibular系统发育的影响和机制.
主要方法:
- 在PubMed和Web of Science上进行全面的文献搜索,截至2024年9月.
- 包括文献评论,系统评论,元分析,临床试验和临床前研究.
- 叙述性审查方法来总结和详细阐述发现.
主要成果:
- 详细了解MB的临床状态及其与TMD的相关性.
- 确定了与MB相关的TMD相关的致病因子和信号通路.
- 信号通路的修改有助于关节组织病理,软骨退化,软骨细胞亡和疼痛.
结论:
- 多个信号通路参与了与MB相关的TMD的病理.
- 未来的研究应该专注于新的动物模型,先进的技术和针对MB相关TMD的有针对性的治疗策略.
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