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Updated: May 12, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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准tRNA甲基转移酶:从分子机制到药物发现

Yanrong Gao1,2, Xinyu Liu1,2, Jiazhi Li3,4

  • 1Institutes of Biomedical Sciences, Inner Mongolia University, Hohhot, 010020, China.

Science China. Life sciences
|May 10, 2025
PubMed
概括

转移RNA甲基转移酶 (tRNA MTases) 是对tRNA稳定性和细胞平衡至关重要的酶. 它们的失调与疾病有关,但抑制剂提供治疗前景.

关键词:
催化机制是一种催化机制.药物开发是药物的发展.在tRNA甲基化过程中,在tRNA甲基转移酶中.在tRNA的识别过程中.

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