在cuprizone模型中,单个脑内脑室内TNFR2激动剂注射会影响复髓化

Valentina Pegoretti1, Ate Boerema1, Kim Kats2

  • 1Department of Molecular Neurobiology, Groningen, Institute of Evolutionary Life Science (GELIFES), University of Groningen, Groningen, The Netherlands.

Journal of molecular medicine (Berlin, Germany)
|May 10, 2025
PubMed
概括

刺激瘤亡因子α受体2 (TNFR2) 促进了脱髓化后的髓修复. 一次治疗减少了非髓质轴突,并支持了寡细胞细胞,这表明神经系统疾病的治疗潜力.