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相关概念视频

Colloidal precipitates01:09

Colloidal precipitates

445
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

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Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
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Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
614

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Updated: May 13, 2025

Monitoring Protein Adsorption with Solid-state Nanopores
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大量纳米泡接口上的离子吸附及其在扩散稳定性中的不确定的作用.

Duncan Dockar1, Patrick Sullivan2, Jacqueline Mifsud3

  • 1School of Engineering, Institute for Multiscale Thermofluids, University of Edinburgh, Edinburgh, EH9 3FB, UK.

Journal of colloid and interface science
|May 10, 2025
PubMed
概括

分子动力学模拟显示,离子吸附于纳米泡表面,形成一个电双层 (EDL). 然而,静电应力并不能稳定纳米泡,这挑战了关于它们长寿命的先前理论.

关键词:
大量的纳米气泡.静电学 静电学 静电学分子动力学模拟的模拟.稳定的稳定性 稳定的稳定性泽塔潜力是一个Zeta潜力.

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科学领域:

  • 物理化学 物理化学
  • 纳米技术 纳米技术
  • 计算科学 计算科学

背景情况:

  • 大量纳米气泡被提议用于诸如水处理和theranostics等应用.
  • 它们的长寿命与经典的泡动力学相矛盾,以静电稳定性作为主要假设.
  • 对负泽塔电位的实验观测支持静电机制.

研究的目的:

  • 研究散装纳米泡的静电稳定机制.
  • 模拟液气界面的离子吸附和泽塔电位,使用模拟.
  • 批判性地研究静电应激在纳米泡寿命中的作用.

主要方法:

  • 高准确度的分子动力学模拟.
  • 在酸电解液溶液中模拟批量纳米泡.
  • 对离子吸附和电双层 (EDL) 形成的分析.

主要成果:

  • 模拟证实了离子吸附和EDL形成,与实验性泽塔电位测量一致.
  • 没有发现显著的静电应力作用于纳米泡表面.
  • 内部气体压力是通过拉普拉斯压力方程准确预测的,即使有托尔曼长度校正.

结论:

  • 拟议的静电应力机制似乎无法稳定散装纳米泡的溶解.
  • 水分子的重新排列中和了EDL内的离子电荷密度.
  • 纳米泡稳定的替代机制需要进一步研究.