结构优化衍生HDAC6异形选择性抑制剂的设计,合成和评估

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Chen Chen1, Xiaochun Ma2, Yichao Wan3

  • 1Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd., Jinan,250100, PR China.

Bioorganic chemistry
|May 10, 2025
PubMed
概括

研究人员开发了一种强效和选择性的HDAC6抑制剂HDSI-18,通过抑制癌细胞增殖而不会引起毒性,显示出抗癌化疗的前景.

关键词:
这是一种抗瘤药物.细胞灭亡 (apoptosis) 是一种死亡的过程.在 HDAC6 中.异形选择性抑制剂异形选择性抑制剂结构优化 结构优化

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