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XCAT 3.0:来自CT扫描的个性化数字双胞胎的一个全面的图书馆

Lavsen Dahal¹, Mobina Ghojoghnejad², Liesbeth Vancoillie²

¹Center for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Department of Radiology, Duke University School of Medicine, Durham, NC, 27708, USA; Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.

Medical image analysis

|May 10, 2025

概括

这项研究引入了一个新的框架,用于生成超过2500个详细的计算幻象,增强虚拟成像试验. 这种自动化方法改善了用于医学成像技术评估的多样化患者解剖学的表示.

科学领域:

医疗成像医学成像
计算建模计算建模
放射学放射学是一门学科.

背景情况:

虚拟成像试验 (VIT) 对于评估医学成像技术至关重要.
当前的计算幻影库缺乏样本大小和异质性,限制了跨不同患者群体的准确评估.
为了实现现实的幻影创建,手工细分是费力和耗时的,阻碍了图书馆的扩展.

研究的目的:

提出一种用于自动创建现实的计算幻影的新框架.
扩大用于研究的各种计算幻象的可用性.
为了提高虚拟成像试验生成幻影的效率和可扩展性.

主要方法:

开发一个框架,利用自动细分模型来生成器官口罩.
针对细分器官口罩的自动化质量控制程序的实施.
产生了超过2500个新的XCAT 3计算幻象,具有140个解剖结构.

主要成果:

发布一个庞大,多样化的图书馆,拥有超过2500个XCAT3计算幻影.
幻影既有发声形式,也有表面网格格式.
框架与CT扫描仪模拟器集成,以产生现实的CT图像.

结论:

开发的框架显著推进了计算幻象的创建.
这有助于更全面,更可靠的虚拟成像试验.
新的幻影图书馆和框架支持对医学成像技术的更广泛评估.

关键词:

计算上的幻影.计算机断层扫描 (CT) 是一种计算机断层扫描.人类数字双胞胎的人类数字双胞胎神经网络的神经网络的神经网络分段化分段化分段化分段化虚拟成像试验的虚拟成像试验

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