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一个模型病毒载体口服薄膜疫苗的热稳定

Annika Yardy1, Iris Q Wang2, Yva Rasco3

  • 1School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada.

International journal of pharmaceutics
|May 10, 2025
PubMed
概括

口服薄膜 (OTF) 提供了一个热稳定疫苗输送方法,在聚合物-糖基质中固定疫苗. 这项研究表明,在OTF中改善了腺病毒载体的稳定性,提高了疫苗的可访问性.

关键词:
实验的设计实验的设计口腔薄膜膜是一种薄膜.热稳定 热稳定 热稳定接种疫苗的交付

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Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...