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Updated: May 14, 2025

Enrichment of Bacterial Lipoproteins and Preparation of N-terminal Lipopeptides for Structural Determination by Mass Spectrometry
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Enrichment of Bacterial Lipoproteins and Preparation of N-terminal Lipopeptides for Structural Determination by Mass Spectrometry

Published on: May 21, 2018

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表面脂蛋白按Gram负细菌中的Lpt和Lol路径之间的交叉分类进行排序

Qingshan Luo1, Chengai Wang1,2, Shuai Qiao1,2,3

  • 1National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.

Nature communications
|May 10, 2025
PubMed
概括

这项研究揭示了一个新的机制,用于运输表面暴露的脂蛋白 (SLPs) 在使用LptDE复合体的阴性细菌LptDE复合体,类似于脂聚糖体 (LPS) 运输. 这一发现表明,在细菌外膜蛋白排序中,Lpt和Lol路径之间存在功能重叠.

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