在使用辅助生殖技术 (ART) 的人群中进行精神药理干预 - - 范围审查
Storman Dawid1, Jemioło Paweł2,3, Adamska Dominika4
1Epidemiology and Preventive MedicineDepartment of Hygiene and DieteticsFaculty of Medicine, Jagiellonian University Medical College, Krakow, Poland. dawid.storman@uj.edu.pl.
Reproductive biology and endocrinology : RB&E
|May 10, 2025
概括
在辅助生殖技术 (ART) 期间使用精神病药物很常见,主要用于抑郁和焦虑. 血清激素再吸收抑制剂经常使用,但证据有限,需要进一步研究.
科学领域:
- 生殖医学 生殖医学
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 不孕症影响六分之一的人,导致许多人使用辅助生殖技术 (ART).
- 在ART期间,焦虑和抑郁是普遍存在的,这凸显了对心理健康支持的需要.
- 关于在接受ART的个体中使用精神药物药物的知识有限.
研究的目的:
- 系统地审查和综合现有的关于在接受ART的个体中使用心理药物治疗的文献.
- 为了确定常见的精神病药物,它们的使用指示,以及在ART患者中报告的结果.
主要方法:
- 在2025年2月之前,对电子数据库进行系统的文献搜索.
- 两个独立审查员选了研究,提取了数据,并解决了冲突.
- 根据药物类别和适用情况进行了描述性分析和子组分析.
主要成果:
- 包括29项研究,抑郁症和焦虑症是药物治疗的主要指示.
- 血清素再吸收抑制剂 (SRIs),特别是素,是研究最多的药物类别.
- 还报告了GABA阳性体调节剂 (midazolam) 和各种抗精神病药物和情绪稳定剂.
结论:
- 在ART中的精神药物治疗主要涉及常见的精神病药物,通常是较低剂量的,首选的是SRIs.
- 证据主要集中在女性身上,目前的数据有限.
- 需要使用标准化的方法进行进一步的研究,以建立明确的治疗模式.
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