大麻使用与精神病医院住院患者自杀强度之间的关联
Adeolu Funso Oladunjoye1,2, Alan Swann1,2, Thomas R Kosten1,2
1Michael E. DeBakey Veterans Affairs (VA) Medical Center, Houston, Texas, USA.
The American journal on addictions
|May 11, 2025
概括
在精神病医院住院患者中,大麻使用 (CU) 与自杀念头强度 (SII) 有不同的关联. 虽然它降低了女性的风险,但它增加了男性的风险,特别是心理灵活性较低的人.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 大麻研究 大麻研究
背景情况:
- 大麻的合法化与日常使用的增加和成年人自杀的死亡相吻合.
- 青少年研究将大麻使用与更高的自杀强度联系起来,但成年人之间的关联仍未得到充分研究.
研究的目的:
- 为了评估大麻使用 (CU) 和自杀念头强度 (SII) 在成人精神病医院住院患者之间的关联.
主要方法:
- 通过使用哥伦比亚-自杀严重性评级尺度和酒精,吸烟和物质参与查测试,对530名成年精神病患者进行了检查.
- 进行了路径分析,以探索缓解/调解因素,如精神病共同疾病,情绪调节,心理灵活性和多基因风险评分.
主要成果:
- 大麻使用 (CU) 与女性 (p=.026) 的自杀念头强度 (SII) 较低相关,但与男性 (p=.525) 不相关.
- 在心理灵活性低的男性中,增加的CU与较高的SII相关 (p=.049),但在女性中没有 (p=.628).
- 在参与者中,16%的人报告没有自杀倾向,34.3%的人有自杀想法,49.6%的人曾经尝试过自杀.
结论:
- 大麻使用 (CU) 与精神病医院住院患者的自杀念头强度 (SII) 增加有关,具有性别特异性的影响.
- 心理灵活性可能会调解男性的CU和SII之间的关系.
- 需要对青春期和成年期的CU模式进行进一步的研究,特别是随着合法化不断扩大.
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