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Updated: May 7, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

从眼科研究翻译到眼科产品

Gary D Novack¹, William J Brock², Audrey R Schupp³

¹PharmaLogic Development, Inc., San Rafael, CA; Department of Ophthalmology & Vision Science, University of California School of Medicine, Davis.

American journal of ophthalmology

|May 11, 2025

概括

本指南帮助学术研究人员将新型眼科药物研究转化为早期开发和临床试验. 它概述了成功开发眼科产品的关键要求.

科学领域:

眼科医生眼科眼科
药物开发药物开发
翻译科学翻译科学

背景情况:

眼科药物开发需要专门的知识.
从研究过渡到临床试验带来了独特的挑战.

研究的目的:

为学术研究人员提供关于开发新型眼科药物的指导.
促进研究转化为早期临床开发.

主要方法:

审查现有指导方针.
纳入作者广泛的产品开发经验.
对化学,非临床,临床和监管方面的要求的陈述.

主要成果:

对药物物质和配方产品的化学要求.
非临床要求包括药理学,药理动力学和毒理学.
临床和监管发展途径.

结论:

成功开发新型眼科产品是一个结构化的过程.
这个过程是顺序和交互的.
本指南支持研究人员在开发途径上进行导航.

关键词:

药物开发美国食品和药物管理局药物开发是药物的发展.眼科药物眼科药物

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Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes

Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes

Published on: February 8, 2018

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

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