爱斯坦-巴尔病毒在周围病变中的存在:系统性审查和元分析
Jagveer Yadav1, Mala Kamboj2, V Gopikrishnan3
1MDS, Post Graduate Student, Department of Oral and Maxillofacial Pathology and Microbiology, Post Graduate Institute of Dental Sciences, Pandit BD Sharma University of Health Sciences, Rohtak, Haryana-124001, India.
Journal of endodontics
|May 11, 2025
概括
爱斯坦-巴尔病毒 (EBV) 与周围病变,尤其是症状病变有显著的关联. 在EBV阳性病例中发现了更高的检测率和更高的风险,这表明EBV在疾病发展中的作用.
科学领域:
- 口腔病理学 口腔病理学
- 传染性疾病传染性疾病.
- 病毒学 病毒学
背景情况:
- 周围病变源于多微生物感染,具有不同的临床症状.
- 爱斯坦-巴尔病毒 (EBV) 在周围疾病发病过程中的作用尚不清楚.
- EBV与各种炎症过程有关.
研究的目的:
- 系统地审查和分析EBV在周围疾病的流行情况.
- 评估EBV在周周病变病变发生的潜在作用.
主要方法:
- 在主要的科学数据库中进行了全面的文献搜索,直到2024年7月.
- 包括专注于EBV和周围疾病之间的关联的研究.
- 用修改的纽卡斯尔-太华尺度评估偏差风险;使用审查经理5.4.4进行元分析.
主要成果:
- 包括31项研究进行了定性综合;15项研究为定量分析做出了贡献.
- 在周周病变中,EBV检测率更高,特别是在症状病例和较大的病变中.
- 分析证实,EBV阳性转录显著增加了周周病变和症状呈现的风险.
结论:
- 在EBV和周周病变之间存在显著的关联,特别是症状和较大的病变.
- 需要进一步的研究来阐明EBV在周围疾病中的致病机制.
- 研究结果表明,对临床管理,包括抗病毒策略的潜在影响.
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