与upadacitinib的联合治疗消除了瘤向IL-2融合蛋白的全身毒性

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Updated: May 15, 2025

Scaled-Up Preparation of an Intermediate of Upatinib, ACT051-3
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Scaled-Up Preparation of an Intermediate of Upatinib, ACT051-3

Published on: April 7, 2023

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Giulia Rotta1,2, Eleonora Prodi1,2, Frauke Seehusen3

  • 1Philochem AG, Otelfingen, Switzerland.

Journal for immunotherapy of cancer
|May 11, 2025
PubMed
概括

将向性互白素-2 (IL-2) 治疗与信号抑制剂相结合,可以提高癌症治疗的耐受性和疗效. 这种方法掩盖了毒性,允许更高,潜在的治疗剂量IL-2.

关键词:
抗体是对抗体的一种.组合疗法是一种联合疗法.细胞因子细胞因子细胞因子释放综合征是什么免疫相关不良事件 - irAEAE

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