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Updated: May 13, 2025

Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake
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Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake

Published on: September 21, 2017

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洞察多巴胺D2受体的干特异激活动态,通过MD模拟进行探索

Samman Mansoor1, Giulia Morra1

  • 1Institute of Chemical Sciences and Technologies (SCITEC), National Research Council (CNR) Via Mario Bianco 9, Milano 20131, Italy.

Journal of chemical information and modeling
|May 12, 2025
PubMed
概括

多巴胺2受体 (D2R) 的结构动力学揭示了像阿里皮普拉和硫皮里德这样的药物如何引起功能选择性. 分子模拟表明,阿里皮普拉可能通过改变受体结构来阻碍阿雷斯结合.

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