相关实验视频
Updated: Jun 5, 2026

10:42
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
儿童及其父母的长期COVID:一项前性队列研究
Hiroyuki Iijima1, Takanori Funaki2, Mitsuru Kubota1
1Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
概括
长期COVID最初影响了近一半的儿童,超过20%的儿童在感染后六个月出现症状. 睡眠障碍显著影响儿童的生活质量.
科学领域:
- 儿科健康 儿科健康
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 长期COVID是一个日益严重的全球健康问题,影响所有年龄组.
- 关于儿科长期COVID特征,患病率和风险因素的纵向数据有限.
研究的目的:
- 纵向评估儿童长期COVID的特征,患病率和危险因素.
- 评估长期COVID症状对儿童生活质量 (QOL) 的影响.
主要方法:
- 一项对108名在日本住院治疗COVID-19的18岁以下儿童及其受影响父母的纵向研究.
- 在住院期间和1,3个月和6个月的随访期间使用的症状问卷.
- 用多变量逻辑回归和协差分析来确定风险因素和质量生活影响.
主要成果:
- 长期COVID的患病率为1个月后的44.9%,3个月后的37.8%,感染后6个月后的22.8%.
- 没有确定儿科长期COVID的特定危险因素.
- 咳,疲劳和睡眠障碍是最常见的;睡眠障碍显著降低了QOL分数.
结论:
- 很大一部分儿童 (22.8%) 在感染SARS-CoV-2后的6个月内出现长期COVID症状.
- 儿童长期COVID症状与肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 标准重叠.
- 长期COVID的症状,特别是睡眠障碍,会对儿童的QOL产生负面影响.
相关概念视频
Lung Capacity
48.1K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
48.1K
Longitudinal Research
11.8K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.8K
Cross-Sectional Research
11.1K
In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
11.1K
Observational Studies
8.1K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.1K
Longitudinal Studies
96
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
96

