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Updated: May 21, 2025

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使用AlphaFold 3辅助拓深度学习对快速病毒进化的快速响应.

JunJie Wee1, Guo-Wei Wei1,2,3

  • 1Department of Mathematics, Michigan State University, East Lansing, MI 48824, United States.

Virus evolution
|May 12, 2025
PubMed
概括

这项研究介绍了一种AlphaFold 3辅助的计算策略,用于预测病毒突变. 该方法准确地预测了结合自由能量的变化,有助于快速应对不断演变的传染性病毒.

关键词:
阿尔法 折叠3 3在SARS-CoV-2变种中.深度突变扫描 (deep mutational scanning) 是一种对突变进行深度扫描的方法.蛋白质蛋白质相互作用拓学深度学习 (deep learning) 是一种学习方式.

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