在亚急性阶段患有严重创伤性脑损伤的个体中经直流刺激:一个案例系列
Barbara Naeme de Lima Cordeiro1, Jader Vinicius Da Silva Rocha1, Elizangela Kuster1
1Neurorehabilitation and Neuromodulation Laboratory, Federal University of Espirito Santo, Vitória, Brazil.
Frontiers in human neuroscience
|May 12, 2025
概括
超直流刺激 (tDCS) 显示出在亚急性阶段改善严重创伤性脑损伤 (TBI) 患者的功能和认知恢复的前景. 这项研究报告了在短时间的tDCS治疗后显著的积极结果.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 严重的创伤性脑损伤 (TBI) 通常会导致长期的功能和认知缺陷.
- 亚急性阶段 (受伤后的2-16周) 是干预以优化恢复的关键时期.
- 目前对TBI的康复策略可能无法完全满足患者的复杂需求.
研究的目的:
- 为了研究在严重的TBI的亚急性阶段的跨直流刺激 (tDCS) 的疗效.
- 评估tDCS对TBI患者功能,认知和心理健康结果的影响.
- 为在TBI康复中应用tDCS提供临床基础.
主要方法:
- 临床病例系列涉及5名男性患者,他们患有严重的TBI (格拉斯哥昏迷表≤8).
- 参与者每天接受5次针对左背侧前额叶皮质 (LPFC) 和逆侧上视圈区域的tDCS治疗.
- 通过使用标准化措施评估结果,包括MMSE,HADS-A,VAS,FIM,RLAS和GOS-E.
主要成果:
- 在tDCS干预后,在多个评估的临床结果中观察到显著的改善.
- 患者表现出认知功能,功能独立性和整体康复状态的改善.
- 这种干预被人很好地容忍,这表明在临床环境中可行性.
结论:
- 跨直流刺激 (tDCS) 显示出作为一种治疗工具的潜力,可以增强严重TBI患者的恢复.
- 这些发现支持在亚急性阶段使用tDCS来改善功能和认知结果.
- 这项研究提供了TDCS在TBI临床管理中的实际应用的初步证据.
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