从卡瓦克罗尔衍生出的N--2-氧胺的合成和抗莱什曼的评估

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Updated: May 5, 2026

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
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A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

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Rayane Luiza de Carvalho1, Alícia da Conceição Terbutino da Silva2, Bianca Muniz Lacerda Ventura1

  • 1Department of Biochemistry and Molecular Biology, Federal University of Viçosa, Avenida Peter Henry Rolfs, s/n, 36570-900 Viçosa, Minas Gerais, Brazil.

ACS omega
|May 12, 2025
PubMed
概括

来自卡瓦克罗尔的新合成化合物显示出对莱什曼病的承诺. 两种新型N-phenyl-2-phenoxyacetamides显示出具有较低毒性的显著抗莱什曼病活性,为这种被忽视的热带疾病提供了潜在的新疗法.

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