PM2.5通过循环AMP-依赖蛋白激酶的途径影响了轴膜的纤毛节拍频率

Jinyan Pang1,2, Zhiqin Xiong1,2, Kexin Zhang1,2

  • 1Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, China.

PubMed
概括

微粒颗粒物 (PM2.5) 暴露会影响呼吸道毛囊. 较低的PM2.5水平刺激了纤毛节拍频率,但高度和长时间暴露可能会损害呼吸器纤毛,增加肺部疾病的风险.

相关概念视频

Setting Time of Cement01:12

Setting Time of Cement

The setting time of cement refers to the process of cement paste transitioning from a plastic state to a solid state. This process is crucial in construction as it dictates the timeframe for concrete placement, compaction, and finishing. The onset of this solidification is termed the initial set, indicating when the paste becomes unworkable. The final set is when the paste has solidified completely, and further handling or manipulation can no longer affect its shape. The cement strength is...
128
Mean free path and Mean free time01:22

Mean free path and Mean free time

Consider the gas molecules in a cylinder. They move in a random motion as they collide with each other and change speed and direction. The average of all the path lengths between collisions is known as the "mean free path."
3.0K
Pulse Assessment Sites01:11

Pulse Assessment Sites

Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
846
Methods of Documentation II: POMR01:26

Methods of Documentation II: POMR

The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
861
Physical Pendulum01:06

Physical Pendulum

When a rigid body is hanging freely from a fixed pivot point and is displaced, it oscillates similar to a simple pendulum and is known as a physical pendulum. The period and angular frequency of a physical pendulum are obtained by using the small-angle approximation and drawing parallels with a spring-mass system. The small-angle approximation (sinθ=θ) is valid up to about 14°.
When dealing with complicated systems, the mass moment of inertia is an important parameter, as it...
1.6K
Instantaneous Power01:22

Instantaneous Power

Instantaneous power is important in electrical circuits, mainly when dealing with sinusoidal input. Instantaneous power, denoted as p(t), results from the multiplication of the instantaneous voltage (v(t)) across an element and the instantaneous current (i(t)) flowing through it. This relationship adheres to the passive sign convention and represents a fundamental principle in electrical engineering.
335