对预测急性缺血性中风后中风相关肺炎的临床评分进行比较
Linlin Wang1, Jun Xu1,2, Xinyu Liu1
1Department of Neurology, Tiantan Hospital Capital Medical University Beijing China.
Aging medicine (Milton (N.S.W))
|May 12, 2025
概括
与其他五种风险评分系统相比,AIS-APS评分在急性缺血性中风后的患者中识别中风相关肺炎 (SAP) 的表现优越. 这一发现有助于SAP更好地评估和管理患者的风险.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 临床流行病学临床流行病学
背景情况:
- 与中风相关的肺炎 (SAP) 是急性缺血性中风 (AIS) 后的常见并发症.
- 对SAP进行准确的风险评估对于及时干预和改善患者结果至关重要.
- 存在多种风险评分系统,但它们在AIS后的SAP预测中的比较性能需要评估.
研究的目的:
- 为了比较六个已建立的风险评分系统的诊断歧视和校准,用于预测AIS后患者的SAP.
- 确定最有效的风险评分来评估这种特定患者群体中的SAP风险.
主要方法:
- 分析了来自第三中国国家中风注册局的12071名患者的验证队列.
- SAP诊断遵循疾病控制和预防中心在医院获得的肺炎的标准.
- 通过使用接收器操作特征曲线 (AUROC) 下的面积和使用Hosmer-Lemeshow测试进行校准来评估歧视.
主要成果:
- 在12,071名患者中,有606人 (5.02%) 患上了住院SAP.
- 在AIS-APS得分中,AUROC是最高的 (0.752),显著比大多数其他得分有更好的歧视,除了PASS得分.
- 该AIS-APS得分还显示了最大的Cox和Snell R2和各种子组的优异歧视,包括年龄,中风严重程度和治疗时间.
结论:
- 这项研究评估了Kwon肺炎评分,A2DS2评分,PANTHERIS评分,AIS-APS评分,ISAN评分和SAP识别的PASS评分.
- 该AIS-APS得分在歧视和校准方面表现最好,用于预测急性缺血性中风后的SAP.
- 建议使用AIS-APS得分作为一种有价值的工具,用于在急性缺血性中风患者中对SAP的风险分层.
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