美容手术后的皮肤非结核菌菌感染:一项回顾性研究
Rui Zeng1,2, Jingshu Xiong1,2,3, Wei Gao4
1Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.
Infection and drug resistance
|May 12, 2025
概括
美容手术后非结核菌菌 (NTM) 引起的皮肤感染正在增加. 早期检测和量身定制的治疗,可能包括手术,对于管理这些具有挑战性的病例至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 医学微生物学 医学微生物学
背景情况:
- 在美容手术后,因非结核菌菌 (NTM) 引起的皮肤感染的报告越来越多.
- 对临床医生来说,诊断和治疗这些NTM感染是一个重大挑战.
研究的目的:
- 检查临床特征,微生物学,组织病理学和NTM感染后化程序的治疗策略.
- 提高临床医生的意识,以便更早地检测和及时治疗与美容学相关的皮肤NTM感染.
主要方法:
- 通过培养或分子鉴定诊断的美容学相关的皮肤NTM感染的回顾性研究.
- 收集的数据包括人口,临床,微生物学,病理活检,管理和结果信息.
- 在中国一家三级皮肤病医院进行的研究.
主要成果:
- 招募了28名患者;24名患者有阳性NTM培养物,主要是快速生长的真菌菌,主要是Mycobacterium综合体 (75%).
- 平均潜伏期为3周,诊断延迟了平均9.8周.
- 治疗通常需要长期的多药疗法;手术可能会缩短疾病的持续时间.
结论:
- 与化品相关的NTM皮肤感染往往被忽视,导致治疗延迟.
- 可以考虑经验性治疗 (克拉里思罗米,莫西弗洛克萨),但敏感性测试至关重要.
- 手术干预和tigecycline (对于耐药病例) 是潜在的治疗选择.
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