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在超重和肥胖儿童中,对积极站立测试的心血管反应
Yasemin Nuran Donmez1, Kutay Sel2
1Department of Pediatric Cardiology, Ankara Training and Research Hospital, Ankara, Türkiye.
Turkish archives of pediatrics
|May 12, 2025
概括
超重和肥胖儿童在活动站立测试中经常经历异常的自主神经系统 (ANS) 反应. 这些静止异常与更高的胰岛素抵抗和HbA1c水平有关,这表明需要在儿科肥胖症中进行ANS评估.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 心血管生理学心血管生理学
- 自主神经系统研究 自主神经系统研究
背景情况:
- 儿童的肥胖和超重与各种健康并发症有关.
- 静止系统异常,或在站立时血压调节的问题,可能会影响心血管健康.
- 自主神经系统 (ANS) 在维持血压和心率稳定方面发挥着至关重要的作用.
研究的目的:
- 评估超重或肥胖儿童的积极站立测试反应.
- 为了确定导致这种儿科患者群体内静止异常的因素.
- 探索肥胖,自主功能和代谢参数之间的关系.
主要方法:
- 通过使用超重和肥胖儿童的活动站立测试来评估正静态反应.
- 监测血压和心率以评估自主神经系统 (ANS) 功能.
- 分析了人体测量测量,实验室参数,包括对胰岛素抵抗的恒常模型评估 (HOMA-IR),胰岛素和HbA1c.
主要成果:
- 在123名超重或肥胖儿童中,有63%的儿童 (平均年龄为15.03岁) 患有静止障碍.
- 在站立测试期间,在59%的参与者中观察到异常反应.
- 检测到正静性低血压,高血压和姿势正静性心动减速综合征,正静组的HOMA-IR,胰岛素和HbA1c水平较高.
结论:
- 儿科肥胖和自主神经系统功能障碍之间存在显著联系.
- 肥胖与儿童中静止性异常的患病率增加有关.
- 在超重或肥胖儿童中评估ANS对于预测和预防不良健康结果至关重要.
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