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Updated: Jun 23, 2026

Selective Capture of 5-hydroxymethylcytosine from Genomic DNA
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Selective Capture of 5-hydroxymethylcytosine from Genomic DNA

Published on: October 5, 2012

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GCfix:一种快速而准确的碎片长度特定的方法,用于纠正无细胞DNA中的GC偏差

Chowdhury Rafeed Rahman1,2, Zhong Wee Poh1,2, Anders Jacobsen Skanderup1

  • 1Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 138672, Singapore.

Bioinformatics (Oxford, England)
|May 12, 2025
PubMed
概括

GCfix是一个新的软件,用于在无细胞DNA (cfDNA) 分析中纠正GC偏差. 它精确地改进了cfDNA碎片学和复制数分析在各种覆盖范围,超过现有方法.

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相关概念视频

Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.