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Updated: May 14, 2025

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上游开放的阅读框架动态调节CLOCK蛋白转换,以调节昼夜节律和睡眠

Yuanqiang Sun1, Ke Shui2,3, Qinyu Li3

  • 1State Key Laboratory of Gene Function and Modulation Research, Center for Bioinformatics, School of Life Sciences, Peking University, Beijing, China.

PLoS biology
|May 12, 2025
PubMed
概括

上游开放读取框架 (uORF) 在Drosophila昼夜钟基因中,特别是Clock (Clk),调节蛋白质翻译. 删除Clk uORFs会缩短昼夜周期并改变睡眠模式.

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