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Updated: May 14, 2025

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系统性失活TREX1诱导瘤微环境的选择性炎症和激活的T细胞介导的瘤控制

Emilija Marinkovic1, Minyi Chen2, Nadja Schubert3

  • 1University Hospital Heidelberg, Germany.

Cancer research
|May 12, 2025
PubMed
概括

抑制宿主细胞中的DNase 3'-修复外核酶1 (TREX1) 增强了抗瘤T细胞免疫力. 这种方法增强了瘤的控制,克服了癌症的免疫逃避,提供了一个有前途的治疗策略.

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