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Updated: Jul 8, 2026

An In vitro Model to Study Heterogeneity of Human Macrophage Differentiation and Polarization
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An In vitro Model to Study Heterogeneity of Human Macrophage Differentiation and Polarization

Published on: June 12, 2013

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心脏巨:从小鼠模型的洞察力到人类研究的翻译潜力

Yufeng Liu1, Tricia T Wang2, Yinsheng Lu3

  • 1Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department, New Haven, CT, USA; Yale Biological and Biomedical Sciences, Graduate School of Arts and Sciences, Yale University, New Haven, CT, USA.

Journal of molecular and cellular cardiology
|May 12, 2025
PubMed
概括

心脏巨细胞 (cMacs) 是心脏健康和疾病中至关重要的免疫细胞. 本综述详细介绍了它们在心血管疾病 (CVD) 中的起源,功能和作用,并比较了小鼠和人类模型.

关键词:
心脏的巨细胞.心血管疾病的心血管疾病.人类 人类 人类 人类 人类巨细胞的功能巨细胞的起源 巨细胞的起源鼠标 鼠标是一个鼠标.

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Isolation and Culture of Resident Cardiac Macrophages from the Murine Sinoatrial and Atrioventricular Node08:43

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...