非结核性真菌菌病死亡率的趋势基于2000-2022年来自83个国家的数据
Ko Harada1, Quynh Thi Vu2, Yoshito Nishimura3
1Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
概括
在2000年至2022年期间,全球非结核性真菌菌菌 (NTM) 感染死亡人数增加了一倍以上,不成比例地影响老年人和女性. 针对性干预对于这种日益严重的公共卫生问题至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 非结核菌 (NTM) 感染是一个日益严重的全球健康问题,特别影响老龄化人口.
- 了解国际死亡率趋势对于公共卫生规划和资源分配至关重要.
研究的目的:
- 分析2000年至2022年与非结核性真菌细菌感染相关的全球死亡趋势.
- 为了确定与NTM相关的死亡率的人口和地理模式.
主要方法:
- 使用世界卫生组织死亡数据库 (83个国家) 的回顾性观察研究.
- 分析与非结核性菌根感染相关的死亡情况,按性别,年龄和地区分层.
- 计算原始和年龄标准化死亡率以评估趋势.
主要成果:
- 在2000年至2022年期间,全球报告了超过42,000起与NTM相关的死亡,其中58.1%为女性.
- 与NTM相关的死亡率增加了一倍多,从每百万个人的0.36到0.77死亡.
- 86%的死亡发生在65岁及以上的人群中,西太平洋地区的死亡率最高.
结论:
- 新型肌肉疾病是一个显著且日益增长的公共卫生挑战,特别是在老年人群中.
- 有针对性的干预措施对于管理和降低NTM感染死亡率至关重要.
- 需要进一步的研究来了解地理差异,并优化治疗策略.
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