儿童出血性中风发病率的检查:一个系统的审查和元分析
Dieu Nguyen1, Sze Wan Cheung1, Yutong Liu1
1Deakin Health Economics, Institute for Health Transformation, School of Health & Social Development, Faculty of Health, Deakin University, Geelong, Victoria, Australia.
概括
儿童出血性中风 (HS) 的发生率在全球范围内有所不同. 创伤伤害显著增加儿童的HS率,突出显示出需要进行病因学研究.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 儿科出血性中风 (HS) 是一个严重的健康问题.
- 儿科HS的全球发病率需要进行彻底的检查.
研究的目的:
- 系统地审查和元分析儿童出血性中风的全球发病率.
- 根据年龄和中风类型来确定发病率的变化.
主要方法:
- 对观察性研究进行了全面的系统审查和元分析.
- 搜索包括主要数据库到2024年3月.
- 数据使用随机效应模型进行了合成,并进行了元回归和偏差评估.
主要成果:
- 包括22篇文章,其中12篇为元分析做出了贡献.
- 发病率各不相同:新生儿 (0.08-1.1/1,000活产),年龄较大的儿童 (0.59-5.1/100,000人年).
- 所有HS的综合发病率为1.45/100,000人/年,在包括创伤伤害在内的研究中,发病率更高.
结论:
- 在创伤和非创伤病例之间观察到HS发病率的显著差异.
- 进一步的研究是必要的,以了解对儿科中风发病率的病因影响.
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