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SARS-CoV-2 感染对喘恶化的长期影响
Kevin E Duong1, Sonya S Henry1, Michael D Cabana2
1Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY.
COVID-19 (SARS-CoV-2) 感染增加了儿童和成人喘恶化的风险. 未满足的社会需求进一步提高了这种风险,突出了针对性预防策略的必要性.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 目前尚不清楚COVID-19对喘恶化的长期影响.
- 评估SARS-CoV-2感染后喘恶化的未来风险对于患者管理至关重要.
研究的目的:
- 评估SARS-CoV-2感染后儿科和成人患者未来喘恶化的风险.
- 确定影响恶化风险的因素,包括人口和社会决定因素.
主要方法:
- 一项回顾性队列研究,涉及12719名SARS-CoV-2喘患者和91,763名对照.
- 根据观察时间,年龄,种族和种族进行匹配分析.
- 安德森-吉尔模型被用来计算复发性喘恶化风险比率 (aHRs),控制并发症和社会需求.
主要成果:
- 与对照组相比,患有喘的COVID-19幸存者表现出明显更高的喘恶化率和风险.
- 儿童在COVID-19后的恶化风险比成年人高.
- 未满足的社会需求与儿童和成人中恶化的风险增加有关.
结论:
- SARS-CoV-2 感染与喘恶化累积发病率较高有关.
- 没有满足社会需求的患者面临着更大的喘恶化风险.
- 临床医生应专注于预防措施,触发器避免,以及疫苗接种对于有COVID-19病史的喘患者.
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