目前关于各种生物材料配方的发展,用于超声中介药物输送
Ji Won Nam1, Badrinathan Sridharan2, Juhyun Kang2
1Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Drug discovery today
|May 12, 2025
概括
超声中介药物输送 (UMDD) 为现代治疗提供了先进的解决方案,克服了各种药物和患者变异性所带来的挑战. 这项技术提高了治疗的有效性,并改善了患者的治疗结果.
科学领域:
- 生物医学工程 生物医学工程
- 药理学 药理学是指药理学的学科.
- 医学物理 医学物理
背景情况:
- 由于现代治疗方法的复杂性和个体患者的差异,传统的药物输送方法面临局限性.
- 越来越需要创新的药物输送系统 (DDS),以提高治疗效率和个性化.
- 超声波 (美国) 技术为推进药物输送方法提供了一个有希望的途径.
研究的目的:
- 审查用于现代治疗的药物输送系统 (DDS) 的最新进展.
- 强调超声波 (美国) 中介药物输送 (UMDD) 在克服当前挑战中的作用和潜力.
- 探索UMDD的机制,材料配方和未来的前景.
主要方法:
- 文献综述,重点关注DDS和UMDD的最新研究.
- 对UMDD背后的热和机械机制的分析.
- 讨论与UMDD兼容的各种材料配方.
- 探索新的视角和潜在的创新在美国指导的药物交付.
主要成果:
- UMDD提供了一个多功能平台,以应对药物交付方面的挑战,包括药物多样性和患者特定需求.
- 超声波的热效应和机械效应都可以利用,以增强药物的透和释放.
- 各种材料配方适合UMDD,扩大其适用性.
- 美国有很大的潜力来创新药物输送,从而改善治疗结果.
结论:
- 超声中介药物输送 (UMDD) 与传统方法相比,是一个显著的进步.
- 通过解决药物和患者的变异性,UMDD提高了治疗的有效性.
- 进一步开发UMDD技术对于改善现代治疗中患者的治疗结果至关重要.
相关概念视频
Factors Influencing Drug Absorption: Pharmaceutical Parameters
123
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
123
Factors Affecting Dissolution: Particle Size and Effective Surface Area
769
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
769
Biopharmaceutics and Pharmacokinetics: Overview
1.9K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
1.9K


