在一般人群中出现新的左心房扩张:四分之一世纪的随访
Cesare Cuspidi1, Rita Facchetti1, Fosca Quarti-Trevano1
1Department of Medicine and Surgery, University of Milano-Bicocca and University Milano-Bicocca Milano, Italy.
European journal of internal medicine
|May 12, 2025
概括
新左心房扩大 (LAE) 影响了超过四分之一的中年成人,受初始心脏大小,体重指数 (BMI) 和BMI和血压在25年内变化的影响. 保持健康的BMI和血压可以预防LAE.
科学领域:
- 心脏病学 心脏病学
- 心血管研究研究心血管研究
- 公共卫生 公共卫生
背景情况:
- 关于左心房扩大 (LAE) 发病率和进展因子的纵向数据有限.
- 在25岁以上的中年成年人中调查新发病的LAE及其决定因素.
研究的目的:
- 为了确定中年成年人中新发 LAE 的发病率.
- 为了确定与LAE发展和25年来的进展相关的因素.
主要方法:
- 对423名参与者的分析,在基线和25年随访时具有心声回声图数据.
- 左心房直径 (LAD) 用二维引导的M模式测量.
- 使用性别特异性和BSA指数的标准来评估LAE.
主要成果:
- 新LAE发生率为27.4% (绝对LAD) 和16.5% (LAD/BSA).
- 最初的LAD,BMI和BMI和LVMI在25年的变化预测了非索引的LAE.
- 对LAE/BSA的可修改预测因素包括最初的LAD/BSA,BMI变化和24小时脉压.
结论:
- 从成年期中期到晚期,LAE的发生率是显著的.
- 最初的LAD,BMI,BMI变化,LVMI和脉压影响LAE.
- 预防肥胖和保持健康的BMI,血压和LVMI是通过减轻LA重塑来预防心血管疾病的关键.
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