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Updated: May 17, 2025

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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[对两例遗传性蛋白C缺乏导致静脉血栓的病例的分析]

M Z Wen1, Y F Lu1, M N Liu1

  • 1Department of Laboratory Medicine, the First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, Wenzhou 325015, China.

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
|May 12, 2025
PubMed
概括

两个PROC基因突变,p.Leu278Pro和p.Trp444Arg,损害了C (PC) 蛋白的功能和分泌,导致静脉血栓形成. 这些发现澄清了PC缺乏和血栓形成风险背后的分子机制.

关键词:
基因突变是一种基因突变.在体外表达.蛋白 C 是一种蛋白质.血栓形成的原因之一是血栓形成.

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