亚皮细胞中的分泌和内细胞分裂支持Trichoderma reesei真菌中尖生长
Martin Schuster1, Sreedhar Kilaru1, Han A B Wösten2
1Department of Biosciences, University of Exeter, Exeter, United Kingdom.
Nature communications
|May 12, 2025
概括
状真菌中的亚皮细胞积极促进状真菌的生长,挑战传统的尖端生长模型. 这些细胞为扩张提供了必不可少的成分,揭示了Trichoderma reesei更复杂的生长机制.
科学领域:
- 菌类学 菌类学是指菌类学.
- 细胞生物学 细胞生物学
- 生物化学 生物化学
背景情况:
- 丝状真菌通过多细胞菌侵入性地生长.
- 枝扩张传统上仅归因于尖生长.
研究的目的:
- 为了研究亚皮细胞在细胞生长中的作用.
- 挑战已有的真菌尖端生长模式.
主要方法:
- 在Trichoderma reesei hyphae的活细胞成像.
- 追踪细胞质流和囊泡运输.
- 可视化1,3-β-葡萄糖合成酶活动.
主要成果:
- 亚皮细胞 (第二到第六) 对于延伸和快速生长率至关重要.
- 外细胞和内细胞发生在顶端和下顶端细胞中.
- 分泌囊泡和内体细胞被双向地穿过体运输.
结论:
- 亚皮细胞积极参与真菌菌根细胞的生长.
- 这些细胞向细胞壁形成的酶和生长供应物输送到状顶部.
- 菌的细胞生长是一个更复杂的过程,涉及协调的亚皮细胞活动.
相关概念视频
Role of Microtubules in Cell Wall Deposition
2.3K
Microtubules are small hollow tubes in eukaryotic cells. The cell wall microtubules are polymerized dimers of two globular proteins, α-tubulin and β-tubulin, two globular proteins. With a diameter of about 25 nm, microtubules are the widest components of the cytoskeleton. They help the cell resist compression and provide a track along which vesicles move through the cell or pull replicated chromosomes to opposite ends of a dividing cell. Microtubules go through quick cycles of...
2.3K
Overview of Secretory Vesicles
7.3K
Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
7.3K
Cell Motility through Blebbing
1.8K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
Blebbing Through the Matrix
In multicellular...
1.8K
Maturation of Endosomes
4.0K
The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB).
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
4.0K
Endocytosis
8.8K
Eukaryotic cells acquire nutrients for growth and proliferation. Nutrients and other molecules that require degradation are internalized from the extracellular space by a process called endocytosis. The term ‘endocytosis' was first coined by Christian de Duve in 1963.
Endocytosis always begins with the plasma membrane enclosing an incoming molecule to form a transport vesicle which, in some cases, can be coated with a protein called ‘clathrin.' Endocytosed material is either...
Endocytosis always begins with the plasma membrane enclosing an incoming molecule to form a transport vesicle which, in some cases, can be coated with a protein called ‘clathrin.' Endocytosed material is either...
8.8K
Vesicular Trasport: Endocytosis, Transcytosis and Exocytosis
748
Vesicular transport is a cellular process that encompasses the engulfment of particles or dissolved substances by cells. It involves endocytosis, transcytosis, and exocytosis.
Endocytosis is a cellular mechanism that involves the inward folding of the cell membrane to create vesicles that capture and transport large drug molecules. This process comprises two distinct methods: pinocytosis (often referred to as "cell drinking") and phagocytosis (often referred to as "cell...
Endocytosis is a cellular mechanism that involves the inward folding of the cell membrane to create vesicles that capture and transport large drug molecules. This process comprises two distinct methods: pinocytosis (often referred to as "cell drinking") and phagocytosis (often referred to as "cell...
748


