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Updated: May 22, 2025

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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双胞胎对分析揭示了DNA甲基化,线粒体DNA数量和肥胖之间的联系

Aino Heikkinen1,2, Vivienne F C Esser3, Seung Hyuk T Lee4

  • 1Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland. aino.heikkinen@helsinki.fi.

Nature communications
|May 12, 2025
PubMed
概括

线粒体DNA数量影响SH3BP4基因甲基化和脂肪组织中的表达,可能影响肥胖. 这项研究将线粒体DNA水平与肥胖特征和SH3BP4甲基化联系起来,表明存在因果关系.

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