使用 CoMiSS 评估 CMP 诱导过敏性乳头炎的婴儿消除饮食的有效性
Menşure Nur Çelik1, Eda Köksal2, Sinem Polat Terece3
1Ondokuz Mayis University, Department of Nutrition and Dietetics, Samsun, Türkiye. mensurenur.celik@omu.edu.tr.
Pediatric research
|May 12, 2025
概括
牛奶蛋白相关症状评分 (CoMiSS) 在消除饮食期间对牛奶蛋白相关的乳头炎 (CMPAP) 婴儿的症状改善的监测显示出希望. 改进,比如专注于哭泣分数,可以提高其临床效用.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏和免疫学 过敏和免疫学
- 临床营养学 临床营养学
背景情况:
- 牛奶蛋白过敏 (CMPA) 在婴儿中很常见,而牛奶蛋白相关的结肠炎 (CMPAP) 是一个特定的表现.
- 目前用于改善CMPA症状的监测工具缺乏关于其有效性的具体数据.
- 牛奶蛋白相关症状评分 (CoMiSS) 是一种临床查工具,对其用于监测CMPA症状解决的使用没有先前的数据.
研究的目的:
- 评估CoMiSS在监测CMPAP患婴儿接受消除饮食的症状改善方面的有效性.
- 为了比较CMPAP婴儿的CoMiSS得分与健康对照的得分.
主要方法:
- 进行了一项随访的病例控制研究.
- 包括被诊断患有CMPAP的婴儿 (n=13) 在消除饮食和17-26周的健康婴儿 (n=22) 中.
- 在四次访问中评估了CoMiSS:6,7,9和12个月的年龄.
主要成果:
- 在CMPAP (p<0.05) 的婴儿接受了为期四周的消除饮食后,CoMiSS得分显著下降.
- 在研究结束时,CMPAP和对照组的总CoMiSS得分都增加了 (p<0.05).
- 哭泣症状得分在CMPAP婴儿中明显高于1和3次访问的对照组 (p<0.05).
结论:
- CoMiSS显示出作为监测CMPAP婴儿饮食反应的工具的潜力.
- 监测特定的分数,如哭泣和开发适合CMPAP的排便分数,可以提高该工具的实用性.
- 进一步完善CoMiSS可能会改善婴儿中CMPAP的临床管理.
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