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用磁力技术分离血细胞:一个批判性审查

Karla Mercedes Paz González1, Linh Nguyen T Tran1, Poornima Ramesh Iyer2

  • 1Department of Chemical Engineering, Texas Tech University, 807 Canton Ave, Lubbock, TX 79409, USA. Jenifer.Gomez@ttu.edu.

Lab on a chip
|May 13, 2025
PubMed
概括

磁分离技术为研究和临床使用提供了高效,低成本的血细胞隔离. 本综述指导了选择有标签和无标签的磁分离方法,以实现最佳的细胞分离和功能保存.

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Overview Of Cell Separation And Isolation01:20

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.