在双胞胎怀孕中,带静脉流量和胎儿联合心脏输出量
Sommart Bumrungphuet1, Katsusuke Ozawa2, Wirada Hansahiranwadee1
1Maternal-Fetal Medicine Division, Obstetrics & Gynaecology Department, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
概括
这项研究确定了双胞胎胎的结合心脏输出 (CCO) 和带静脉流量 (UVFV) 的正常参考范围. 这些关键的血液动力学参数在单胆双胞胎和双胆双胞胎之间没有差异.
科学领域:
- 周围生理学 周围生理学
- 胎儿医学 胎儿医学
- 心血管生理学心血管生理学
背景情况:
- 准确评估胎儿血液动力学对于监测双胞胎怀孕至关重要.
- 在双胞胎中,为结合心脏输出 (CCO) 和带静脉流量 (UVFV) 建立正常参考范围对于临床实践至关重要.
- 了解单双胞胎和双双胞胎之间的潜在差异需要特定的数据.
研究的目的:
- 为了在怀孕20至28周之间的双胞胎胎中确定CCO和UVFV的正常参考范围.
- 为了评估和比较CCO和UVFV之间的双胞胎和双胞胎双胞胎怀孕.
- 为了评估体重校正的UVFV (UVFV/kg) 和CCO (CCO/kg) 的稳定性以及UVFV与CCO的比率在这个妊娠期.
主要方法:
- 在两个中心进行了对CCO和UVFV的前性超声波测量.
- 从274个胎儿收集了UVFV和269个胎儿收集了CCO的数据,测量分为三个妊娠年龄组 (20-22,23-25,26-28周).
- 严格的排除标准被应用以确保健康的研究人群,排除诸如胎儿生长限制和双胞胎特异性综合征等条件.
主要成果:
- 随着孕期的推进,UVFV和CCO都增加了,而体重校正后的UVFV/kg和CCO/kg保持稳定.
- 在单和二双胞胎胎之间没有观察到UVFV或CCO的显著差异.
- 平均UVFV/kg为127.8±31.8毫升/公斤/分钟,CCO/kg为439.4±80.1毫升/公斤/分钟,UVFV与CCO比率稳定 (27.7%31.8%).
结论:
- 在怀孕20至28周的双胞胎胎中,已确定CCO和UVFV的正常参考范围.
- 单和二双胞胎胎在CCO和UVFV方面表现出类似的血液动力学特征.
- 已建立的范围和发现支持在双胞胎怀孕的常规胎儿监测中使用这些参数.
相关概念视频
Fetal Circulation
634
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
634
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
529
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
529
Cardiac Output and Stroke Volume
2.5K
Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical...
In an average resting adult male, the typical...
2.5K
Venous Return
2.3K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
2.3K
Pulse
668
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
668
Coronary Circulation
1.8K
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
1.8K


