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Updated: May 15, 2025

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NINJ1和MMP9:内动脉样硬化斑块脆弱性的潜在生物标志物

Xiao-Lian Wei1,2, Xin Da1, Yu-Ge Zhang1,2

  • 1Department of Neurology II, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.

Frontiers in neurology
|May 13, 2025
PubMed
概括

血清神经损伤诱导蛋白1 (NINJ1) 和矩阵金属蛋白酶9 (MMP9) 是脆弱的内动脉样硬化斑块的独立预测剂. 这些生物标志物显示出在ICAS患者中识别斑块增强,严重狭窄和积极重塑的潜力.

关键词:
高分辨率的容器墙壁成像矩阵金属蛋白酶 9 9神经损伤引起的蛋白质1标志性斑块 标志性斑块 标志性斑块有症状的内动脉样硬化狭窄症.

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
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