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Updated: Jul 29, 2026

A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion
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启用SuFEx的高吞吐量药物化学,用于开发强大的他莫西芬类型,作为埃博拉病毒进入抑制剂

Lucas Dada1, Emiko Nagai1, Sashank Agrawal2

  • 1Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, United States.

Frontiers in immunology
|May 13, 2025
PubMed
概括

研究人员优化了埃博拉病毒进入抑制剂塔莫西芬,使用硫交换点击化学. 这种高通量方法迅速产生了强大的小分子抗病毒药物来对抗埃博拉病毒疾病.

关键词:
埃博拉病毒埃博拉病毒.SuFEx SuFEx 是一个直接进入生物学.发现药物的发现.小分子抗病毒药物 小分子抗病毒药物

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