怀孕期间使用大麻与不利的母亲心理健康结果相关:一项回顾性研究
Kypros J Dereschuk1, Eduardo Espiridion2
1Psychiatry, Drexel University College of Medicine, Philadelphia, USA.
Cureus
|May 13, 2025
概括
怀孕期间使用大麻与母亲患抑郁症,恐慌症,自杀念头和滥用酒精的风险更高有关. 医疗保健提供者应对产前大麻使用和心理健康问题进行查.
科学领域:
- 产科和妇科 产科和妇科
- 围产期心理健康 围产期心理健康
- 公共卫生 公共卫生
背景情况:
- 怀孕期间使用大麻的数量随着合法化而增加.
- 感知到的安全性可能会导致用于怀孕不适.
- 潜在的不良母亲心理健康影响越来越令人担忧.
研究的目的:
- 评估在怀孕期间使用大麻与母亲心理健康结果之间的关联.
- 量化抑郁症,恐慌症,自杀念头和滥用酒精的风险.
主要方法:
- 使用TrinetX数据库 (超过200万名孕妇) 的回顾性队列研究.
- 与 51,087 名孕妇大麻使用者和 1,936,508 名非使用者进行了比较.
- 使用ICD-10代码分析了心理健康结果;计算了风险和危险比率.
主要成果:
- 怀孕期间使用大麻与所有四种心理健康结果的发病率增加有显著的关联.
- 滥用酒精 (RR 13.57) 和自杀念头 (RR 10.67) 显示了最高的相对风险.
- 使用者中抑郁率为29.7%,非使用者为11.2% (p < 0.001).
结论:
- 产前大麻使用与母亲的不良心理健康结果有显著的联系.
- 强调需要在怀孕期间对大麻使用和心理健康状况进行查.
- 强调需要开展关于产前大麻暴露风险的公共卫生倡议.
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