首次报告Tannerella forsythia感染在患有广泛支气管切除症的患者身上:一个病例报告
Congli Fu1, Yilan Sun1, Chun Chen1
1Cancer Center, Department of Pulmonary and Critical Care Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Frontiers in medicine
|May 13, 2025
概括
在口腔疾病中常见的细菌Tannerella forsythia被确定为支气管病患者严重肺部感染的原因. 这一案例突出显示了一种罕见的肺部感染及其成功治疗.
科学领域:
- 微生物学 微生物学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 丹尼雷拉 (Tannerella forsythia) 是牙周病的已知病原体.
- 很少有人报告T.forsythia引起的肺部感染.
- 支气管切除症是一种慢性肺部疾病,其特点是呼吸道受损.
研究的目的:
- 报告一种罕见的,感染Tannerella forsythia的支气管炎病例.
- 描述这种感染的诊断方法和治疗方法.
- 突出T.forsythia在肺部疾病中的潜在作用.
主要方法:
- 一位患有支气管切除症的患者出现呼吸系统症状.
- 胸部计算机断层扫描 (CT) 用于评估肺部参与.
- 支气管洗液 (BAL) 的下一代元基因组测序 (mNGS) 确定了致病原体.
- 患者接受了抗生素治疗.
主要成果:
- 在BAL液体的mNGS中,主要检测到Tannerella forsythia.
- 患者表现出发烧,咳,唾液产生和呼吸短促等症状.
- 胸部CT显示了双边肺支气管切除与传染性迹象.
- 用Piperacillin-tazobactam和ornidazole治疗导致了有利的临床结果.
结论:
- 丹尼雷拉福西西亚可能会在患有支气管切除症的患者中引起严重的肺感染.
- mNGS是识别呼吸道感染中罕见病原体的宝贵工具.
- 及时诊断和适当的抗生素治疗对于管理T.forsythia肺部感染至关重要.
更多相关视频
07:08A Rapid, Multiplex Dual Reporter IgG and IgM SARS-CoV-2 Neutralization Assay for a Multiplexed Bead-Based Flow Analysis System
Published on: April 6, 2021
4.9K
05:21Author Spotlight: Optimizing Antibody-Based Cancer Treatments via Antibody-Dependent, Cell-Mediated Cytotoxicity Assay
Published on: September 13, 2024
230
相关概念视频
01:29Pulmonary Tuberculosis I
1.7K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.7K
01:28Pulmonary Tuberculosis II
2.5K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.5K
01:31Pulmonary Tuberculosis III
1.8K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
1.8K
01:26Pulmonary Tuberculosis IV
828
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
828
01:28Pulmonary Tuberculosis V
1.0K
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
1.0K
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
40
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
40