构建和验证结直肠状状病变的风险名录模型
Sihui Huang1, Shiyu Liu1, Fang Tan1
1The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, China.
The Journal of international medical research
|May 13, 2025
概括
确定结直肠状形病变的危险因素至关重要. 年龄,吸烟,酒精消费和甘油三-葡萄糖指数是关键预测因素,为新的风险名组模型提供信息.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 结肠直肠状状病变 (SSL) 是结肠直肠癌的前体.
- 准确的SSL风险分层对于早期检测和预防至关重要.
研究的目的:
- 为了确定结直肠状状病变的独立风险因素.
- 开发和验证SSL风险的预测名ogram模型.
主要方法:
- 追溯队列研究,包括2019年1月至2023年9月的患者.
- 单变量和多变量逻辑回归分析以确定预测因素.
- 使用培训和验证集 (7:3比) 构建和验证Nomogram模型.
主要成果:
- 年龄,吸烟史,酒精消费史和甘油三指数被确定为SSL的独立风险因素 (p < 0.05).
- 诺米图表表现出良好的预测性能,AUC值为0.715 (训练组) 和0.742 (验证组).
- 校准曲线和决策曲线分析显示了良好的准确性和临床实用性.
结论:
- 年龄,吸烟,酒精消费和甘油三糖指数是结直肠状状病变的重要预测因素.
- 开发的诺莫格拉姆模型显示了预测SSL个体风险的潜力,有助于临床决策.
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