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深度依赖色彩编码的光学衰减系数成像:面部微循环的辅助检查方法

Jian Liu¹, Linghui Kong¹, Binyin Zhang¹

¹School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao City, China.

Journal of biophotonics

|May 13, 2025

概括

这项研究将面部微循环与皮肤光学特性联系起来,使用扫描源光学连贯性断层扫描 (SS-OCT). 研究结果揭示了血流如何改变光学衰减,使皮肤健康评估的新成像工具成为可能.

科学领域:

生物医学光学生物医学光学
皮肤病学皮肤病学
医疗成像医学成像

背景情况:

面部微循环的下降会影响皮肤健康,导致血液停滞和代谢问题.
皮肤的光学特性,如散射和衰减,受到微循环变化的影响.
光学连贯断层扫描 (OCT) 是一种非侵入性成像技术,用于可视化地下组织结构.

研究的目的:

研究面部微循环与光学参数之间的关系.
探索不同皮肤层中血流和光学衰减系数 (OAC) 之间的相关性.
开发一种增强的成像方法来可视化面部微循环.

主要方法:

使用高分辨率扫描源光学连贯性断层扫描 (SS-OCT) 进行成像.
在表皮和皮肤层分析了血液流量测量和光学衰减系数 (OAC) 之间的相关性.
开发并实施了一个深度编码的彩色OAC成像模式.

主要成果:

在表皮OAC和血液流量之间观察到负相关性 (r = -0.29 ± 0.03).
在皮肤OAC和血流之间发现了正相关性 (r = -0.43 ± 0.06).
新的深度编码彩色OAC成像模式改善了微循环可视化,没有额外的扫描.

结论:

建立了对微循环相关皮肤恶化的机制性见解.
证明OAC随着皮肤深度的血液流动而变化.
引入了一种新的临床工具,用于诊断和管理与微循环相关的皮肤疾病.

关键词:

深度依赖成像的成像方法面部微循环的方法光学衰减系数的光学衰减系数光学连贯性断层扫描 (optical coherence tomography) 是一种光学连贯性断层扫描技术.

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