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Updated: May 16, 2025

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
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通过iKIR-HLA-C轴对母胎界面的γδT细胞退化进行研究

Diana Manchorova1, Marina Alexandrova1, Antonia Terzieva1

  • 1Institute of Biology and Immunology of Reproduction "Acad. Kiril Bratanov", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.

Cells
|May 13, 2025
PubMed
概括

母胎耐受性涉及抑制性杀手细胞免疫球蛋白类受体 (iKIR) 在gδT细胞上,与热囊细胞上的HLA-C相互作用. 早期怀孕显示增加了iKIR阳性γδT细胞和HLA-C表达,但热囊细胞不会抑制γδT细胞的细胞毒性.

关键词:
在 HLA-C 的情况下.脱粒化和脱粒化的方法人类怀孕的人类怀孕抑制性的KIRs.的 γδT 细胞.

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Transcytosis of IgG01:15

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Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
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