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Updated: May 14, 2025

07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
7.9K
[儿童和青少年对蜜蜂和黄蜂毒液过敏]
Michael Gerstlauer1, Lars Lange2, Sunhild Gernert2
1Kinderpneumologie/päd. Allergologie, Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Augsburg, Stenglinstraße 2, 86156, Augsburg, Deutschland. michael.gerstlauer@uk-augsburg.de.
Dermatologie (Heidelberg, Germany)
|May 13, 2025
概括
对于经历过疹症以外的过敏反应的儿童,建议使用虫毒液免疫疗法 (AIT). 三年的AIT显著减少了严重的过敏反应,可能消除了急救套装的需要.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 儿科医学 儿科医学
- 毒理学 毒理学 毒理学
背景情况:
- 黄虫刺伤可以引起过敏反应,需要进行诊断程序.
- 儿童的系统性过敏反应具有较低的后续刺痛严重反应风险.
- 目前的指导方针建议诊断测试和治疗的具体适应症.
研究的目的:
- 为了确定在黄斑虫毒素敏感化中的诊断程序的标准.
- 建立针对儿童的过敏原免疫疗法 (AIT) 和急救套装的指示.
- 评估AIT在预防严重反应方面的有效性.
主要方法:
- 检查对海门虫毒素敏感化的诊断程序的审查.
- 分析儿童刺痛后严重反应的危险因素.
- 对接受AIT治疗的儿童与未接受治疗的儿童的结果的评估.
主要成果:
- 只有在导致AIT的情况下,才应该进行毒素敏感化的诊断程序.
- 只有局部反应或疹的儿童通常不需要AIT或急救套装.
- 在儿童中,除疹外的过敏反应需要AIT和急救包,AIT可以降低严重反应的风险.
结论:
- 过敏原免疫疗法 (AIT) 适用于小儿海门虫毒液过敏症,超出疹症.
- 至少三年的AIT有效预防严重的过敏反应.
- 刺痛挑通常不建议用于儿童的诊断或治疗监测.
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