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Updated: Jun 14, 2026

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells
10:02

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells

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补充剂C5a通过SLC38A1介导的谷氨胺代谢促进人类视网膜色素上皮细胞的活力和迁移

Ye Sun1, Yifan Hu1, Shasha Luo2

  • 1Jiangnan University Wuxi School of Medicine, Wuxi No.2 People's Hospital (Jiangnan University Medical Center), Wuxi, 214000, China.

Medical microbiology and immunology
|May 13, 2025
PubMed
概括

补充因子C5a通过增加SLC38A1表达来增强视网膜色素表皮 (RPE) 细胞活力和迁移,影响谷氨胺代谢. 这一途径涉及METTL3介导的m6A修饰,突出了视觉障碍的新治疗标.

关键词:
补充 C5a 补充谷氨胺的代谢过程在METTL3中,METTL3是METTL3的第一个类型.视网膜色素表皮细胞的细胞表皮.在 SLC38A1 中.

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