在无症状的参与者中,休息45分钟的仰卧状态产生了一致的基线腰椎椎间盘高度
Nicole E Zimmer1,2, James A Coppock1,2, Andrzej S Kosinski3,4
1Department of Orthopaedic Surgery, School of Medicine, Duke University, Durham, NC, 27710, USA.
Annals of biomedical engineering
|May 13, 2025
概括
45分钟的休息时间为测量腰椎间盘 (IVD) 高度提供了可靠的基线,无论一天中的时间如何. 这种一致性对于准确的体内IVD力学研究至关重要.
科学领域:
- 生物力学 生物力学
- 脊椎解剖学 脊椎解剖学
- 医疗成像医学成像
背景情况:
- 椎间盘 (IVD) 高度表现出由于脊柱负荷变化的日间波动.
- 准确的体内IVD高度测量需要考虑先前的加载历史.
- 现有的文献缺乏关于在低负荷下体内腰部IVD高度恢复时间的共识.
研究的目的:
- 为了确定45分钟的仰卧休息期是否为体内腰部IVD高度测量建立了一致的基线.
- 评估IVD在一天中不同时间的高度测量的可靠性.
主要方法:
- 九名健康参与者在45分钟的卧卧休息后接受了磁共振成像 (MRI).
- 图像测试是在两个不同的时间进行的:早上 (7:00 AM) 和中午 (10:30 AM-12:30 PM).
- 腰部IVD高度 (L1-L2到L5-S1) 被手动细分和测量;细分的重复性也被评估.
主要成果:
- 在一天中不同时间的IVD高度测量 (ICC:0.96) 和分段重复性 (ICC:0.97) 中观察到高可靠性.
- 根平均平方误差 (RMSE) 是最小的 (0.08毫米),占IVD总高度的不到1%.
结论:
- 一个45分钟的卧底休息时间足以建立一个一致和可靠的基线来测量体内腰部IVD高度.
- 这些发现支持使用该协议在早上7点到下午12点30分之间进行精确的IVD力学研究.
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