3岁以下自闭症的家长调解干预:系统性审查,元分析和主持人分析
Xiaoqian Zhao1, Fengyi Kuo2,3, Xiangyu Chen1
1Beijing University of Chinese Medicine, Fangshan District, Beijing, 102401, China.
Journal of autism and developmental disorders
|May 13, 2025
概括
3岁以下的自闭症谱系障碍 (ASD) 的早期干预显示出很小的益处,特别是在适应能力和父母互动方面. 然而,证据质量中等至低,需要谨慎解释和进一步研究.
科学领域:
- 发展心理学 发展心理学
- 儿科医学 儿科医学
- 临床心理学 临床心理学
背景情况:
- 早期干预对于3岁以下患有自闭症谱系障碍 (ASD) 的儿童至关重要.
- 父母介导干预 (PMI) 是一种常见的方法,但其有效性和影响因素需要彻底评估.
研究的目的:
- 评估家长介导干预 (PMI) 对3岁以下自闭症儿童的有效性.
- 探索潜在的调节者,影响这些干预措施的有效性.
主要方法:
- 来自五个英语数据库的随机对照试验 (RCT) 的系统审查和元分析.
- 随机效应模型用于元分析 (Hedges's g),用于小组分析和调节者的元回归.
- 使用GRADE标准评估证据质量.
主要成果:
- 在3年以下的ASD中发现了PMI的小整体有益作用 (g=0.20).
- 观察到的积极影响包括适应能力,家长反应能力,亲子互动,社交沟通和症状严重程度.
- 没有对认知能力,语言或运动技能的显著影响;没有调节者显著影响了有效性. 证据质量从中等到低不等.
结论:
- PMI对患有自闭症的幼儿产生积极影响,特别是在特定的发育领域.
- 证据的确定性中等至低,需要谨慎地解释研究结果.
- 未来的研究应该专注于大规模,多中心,高质量的临床研究来证实这些影响.
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